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Molecular Mechanisms for a Novel Class of Openers Targeting Voltage- and Calcium-activated Potassium Channels. [Clear]

# Title Funder Funding Start End Status
1 An in vitro human cell assay to investigate the effects of psychiatric risk gene CACNA1C dosage on neuronal network activity MRC
£0
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2 Subunit specific mechanisms by which potassium channels mediate intrinsic plasticity and neuronal integration in the auditory pathway BBSRC
£1,441,012
 Feb. 1, 2018 Jan. 31, 2022 Closed
3 Molecular mechanisms of voltage-gated potassium channel clustering in myelinated axons BBSRC
£1,173,476
 March 31, 2020 March 30, 2023 Active
4 Effects of neurotransmitters on axonal KV7 channel function in hippocampal neurons BBSRC
£724,242
 April 29, 2014 July 30, 2018 Closed
5 Single neuron computation MRC
£3,429,092
 Nov. 1, 2002 Dec. 31, 2009 Closed
6 Intrinsic plasticity of neuronal excitability in the auditory brainstem and neocortex: nitrergic signalling to voltage-gated potassium channels MRC
£1,384,778
 Feb. 4, 2013 July 30, 2016 Closed
7 Role of A- and M-type K+ and Ih currents and channels in spontaneous pain MRC
£748,288
 Dec. 1, 2007 May 30, 2011 Closed
8 Finding treatments for drug-resistant epilepsy: a novel drug discovery approach based on diverse model organisms. MRC
£0
 Sept. 30, 2016 March 30, 2020 Closed
9 Novel gene therapy strategy for refractory epilepsy MRC
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 Sept. 24, 2017 Sept. 29, 2021 Closed
10 The role of alpha3-GABAA receptors in mono-aminergic neuronal function BBSRC
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11 All-optical electrophysiology: probing real-time dynamics of neural circuits BBSRC
£813,030
 May 31, 2022 May 30, 2025 Active
12 Modelling the safety factor in neuromuscular transmission using 'population of models' approach MRC
£0
 Aug. 31, 2017 July 30, 2022 Active
13 Multi-protein assembly of intracellular ion-sensitive potassium channel complexes BBSRC
£465,868
 April 30, 2006 April 29, 2009 Closed
14 Integration of calcium signalling mechanisms in neural modelling BBSRC
£514,446
 March 1, 2011 Feb. 28, 2014 Closed
15 The neural basis of descending motor control BBSRC
£0
 Sept. 26, 2020 Oct. 31, 2024 Active
16 The genetic architecture and functional role of the mitochondrial transcriptome in the Human Brain BBSRC
£0
 Sept. 26, 2021 Sept. 29, 2025 Active
17 The genetic architecture and functional role of the mitochondrial transcriptome in the Human Brain BBSRC
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 Sept. 30, 2021 Sept. 30, 2025 Active
18 Fragile X mental retardation protein interaction with neuronal voltage-gated calcium channels: mechanism and consequences MRC
£1,661,120
 Dec. 1, 2012 Nov. 30, 2015 Closed
19 Electrophysiological-mechanical coupled pulses in neural membranes: a new paradigm for clinical therapy of SCI and TBI (NeuroPulse) EPSRC
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20 Proteolytic processing of sodium channel beta1 subunits BBSRC
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