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Molecular Mechanisms for a Novel Class of Openers Targeting Voltage- and Calcium-activated Potassium Channels. [Clear]

# Title Funder Funding Start End Status
41 Structure and Function of the Human 1.8 Voltage-Gated Sodium Channel Associated with Pain Sensation BBSRC
£1,161,336
 Sept. 30, 2017 Sept. 29, 2021 Closed
42 Amnesia and the medial temporal lobes: an investigation in autoimmune limbic encephalitis MRC
£2,255,798
 Aug. 2, 2013 April 1, 2019 Closed
43 Modulation of synaptic transmission by presynaptic receptors in the cerebral cortex MRC
£2,640,516
 Jan. 2, 2001 March 30, 2009 Closed
44 Parallel electrophysiological characterization of sodium channels EPSRC
£1,067,438
 Sept. 30, 2010 Sept. 29, 2014 Closed
45 Parallel electrophysiological characterization of sodium channels EPSRC
£956,988
 May 31, 2010 May 30, 2014 Closed
46 Investigating coupling of metabolism with gene transcription to support the axonal regeneration programme for repair MRC
£4,094,990
 March 1, 2023 Aug. 31, 2026 Active
47 Chimeric Human-NavMs Sodium Channel Constructs for Structure/Function Studies of Selective Toxin Binding BBSRC
£0
 Sept. 22, 2019 Sept. 29, 2023 Active
48 Structure and Function of Voltage-Gated Ion Channels and their Applications for Rational Drug Design BBSRC
£1,064,830
 March 30, 2014 Sept. 29, 2018 Closed
49 Elucidating early stage ALS pathomecanisms that drive mitochondrial dysfunction MRC
£1,701,162
 Jan. 1, 2020 May 6, 2023 Active
50 Elucidating early stage ALS pathomecanisms that drive mitochondrial dysfunction MRC
£4,252,905
 Jan. 1, 2020 May 7, 2023 Closed
51 CBET-EPSRC: Hybrid organic-CMOS devices for optogenetic simulation and lens-free fluorescence imaging of the brain EPSRC
£767,072
 Aug. 31, 2017 Nov. 16, 2020 Closed
52 Exploitation of a Pharmacological 'Master Switch' to Probe the K+ Channel Selectivity Filter Gating Mechanism BBSRC
£817,418
 March 1, 2019 June 29, 2022 Closed
53 Role of HCN ion channels in pain BBSRC
£145,080
 Sept. 30, 2008 Sept. 29, 2012 Closed
54 Structural Basis of Sigma-1 Receptor Ligand Interactions and Signalling MRC
£1,250,464
 April 1, 2013 March 31, 2016 Closed
55 Structural Basis of Sigma-1 Receptor Ligand Interactions and Signalling MRC
£3,126,160
 April 1, 2013 April 1, 2016 Closed
56 TRAK-mediated neuronal mitochondrial trafficking mechanisms: regulation and impact on neuronal function BBSRC
£1,289,912
 Nov. 6, 2013 Aug. 4, 2017 Closed
57 TRAK-mediated neuronal mitochondrial trafficking mechanisms: regulation and impact on neuronal function BBSRC
£3,224,780
 Nov. 6, 2013 Aug. 5, 2017 Closed
58 Probing the dynamics of agonist drug interaction with Cys-loop channels by single-molecule recording MRC
£1,076,130
 Nov. 1, 2012 April 29, 2016 Closed
59 Modulation of thermo-TRP ion channel activity by phosphorylation and trafficking to the membrane BBSRC
£779,192
 Jan. 1, 2008 Dec. 31, 2010 Closed
60 Modulation of thermo-TRP ion channel activity by phosphorylation and trafficking to the membrane BBSRC
£1,947,980
 Jan. 1, 2008 Dec. 31, 2010 Closed
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