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Structure and Function of the Human 1.8 Voltage-Gated Sodium Channel Associated with Pain Sensation [Clear]

# Title Funder Funding Start End Status
1 Parallel electrophysiological characterization of sodium channels EPSRC
£956,988
 May 31, 2010 May 30, 2014 Closed
2 Parallel electrophysiological characterization of sodium channels EPSRC
£1,067,438
 Sept. 30, 2010 Sept. 29, 2014 Closed
3 Crystal structure analysis of a voltage-gated sodium channel BBSRC
£1,026,592
 April 30, 2010 June 29, 2014 Closed
4 Role of A- and M-type K+ and Ih currents and channels in spontaneous pain MRC
£748,288
 Dec. 1, 2007 May 30, 2011 Closed
5 Regulation of cancer cell migration by voltage-gated sodium channels MRC
£1,533,962
 Jan. 17, 2011 Jan. 16, 2016 Closed
6 Glycosylphosphatidylinositol (GPI)-anchoring of calcium channel alpha2delta subunits: function and pharmacology MRC
£1,929,610
 April 30, 2011 Oct. 30, 2015 Closed
7 Molecular mechanisms of voltage-gated potassium channel clustering in myelinated axons BBSRC
£1,173,476
 March 31, 2020 March 30, 2023 Active
8 Exploitation of a Pharmacological 'Master Switch' to Probe the K+ Channel Selectivity Filter Gating Mechanism BBSRC
£817,418
 March 1, 2019 June 29, 2022 Closed
9 Probing the dynamics of agonist drug interaction with Cys-loop channels by single-molecule recording MRC
£1,076,130
 Nov. 1, 2012 April 29, 2016 Closed
10 The molecular basis of target site and metabolic insecticide resistance BBSRC
£1,146,221
 March 31, 2008 March 30, 2012 Closed
11 Cellular Dynamics of Voltage-Gated Calcium Channels: Control Via Gabapentinoid-sensitive Auxiliary Alpha2-Delta Subunits MRC
£1,167,304
 Jan. 14, 2008 April 12, 2011 Closed
12 Structure and Function of Voltage-Gated Ion Channels and their Applications for Rational Drug Design BBSRC
£1,064,830
 March 30, 2014 Sept. 29, 2018 Closed
13 Role of HCN ion channels in pain BBSRC
£145,080
 Sept. 30, 2008 Sept. 29, 2012 Closed
14 Role of LGI and ADAM proteins in the functional organization of the myelinated axon BBSRC
£0
 Sept. 30, 2017 Sept. 29, 2021 Closed
15 Role of voltage-dependent calcium channels in nociceptive transmission under normal and neuropathic conditions BBSRC
£465,984
 Jan. 1, 2007 Dec. 31, 2009 Closed
16 Peripheral voltage gated sodium channels in health and disease MRC
£2,729,948
 May 31, 2010 April 29, 2016 Closed
17 MICA: A comprehensive genomic and functional approach to discover new ion channel targets for human pain treatment MRC
£1,997,354
 Sept. 30, 2012 June 29, 2016 Closed
18 Microsystems for coupled expression and electrophysiology of ion channels EPSRC
£203,872
 June 22, 2011 Nov. 29, 2013 Closed
19 A Functional Analysis of Resistance to Pyrethroid Insecticides in the malaria vector Anopheles gambiae MRC
£841,094
 March 1, 2022 Feb. 28, 2025 Active
20 Proteolytic processing of sodium channel beta1 subunits BBSRC
£0
 Sept. 30, 2015 Sept. 29, 2019 Closed
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