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The human Nav1.1 sodium channel: Structure, Function, Drug Binding and Molecular Dynamics of Homologues Bearing Disease-Related Mutations [Clear]

# Title Funder Funding Start End Status
1 Microsystems for coupled expression and electrophysiology of ion channels EPSRC
£203,872
 June 22, 2011 Nov. 29, 2013 Closed
2 Voltage-independent calcium entry and its role in the differentiation of neuronal cancer cell phenotypes MRC
£677,434
 July 8, 2007 Nov. 8, 2010 Closed
3 Multi-protein assembly of intracellular ion-sensitive potassium channel complexes BBSRC
£465,868
 April 30, 2006 April 29, 2009 Closed
4 Structure and Function of the Human 1.8 Voltage-Gated Sodium Channel Associated with Pain Sensation BBSRC
£1,161,336
 Sept. 30, 2017 Sept. 29, 2021 Closed
5 Parallel electrophysiological characterization of sodium channels EPSRC
£956,988
 May 31, 2010 May 30, 2014 Closed
6 Parallel electrophysiological characterization of sodium channels EPSRC
£1,067,438
 Sept. 30, 2010 Sept. 29, 2014 Closed
7 Proteolytic processing of sodium channel beta1 subunits BBSRC
£0
 Sept. 30, 2015 Sept. 29, 2019 Closed
8 Glycosylphosphatidylinositol (GPI)-anchoring of calcium channel alpha2delta subunits: function and pharmacology MRC
£1,929,610
 April 30, 2011 Oct. 30, 2015 Closed
9 Adaptive Multi-Resolution Massively-Multicore Hybrid Dynamics EPSRC
£1,991,140
 Sept. 4, 2011 Sept. 4, 2013 Closed
10 CORSICA: Navigating at will the siliCOn-caRbon phaSe dIagram via maChine leArning EPSRC
£0
 Sept. 30, 2018 Sept. 29, 2022 Active
11 Chimeric Human-NavMs Sodium Channel Constructs for Structure/Function Studies of Selective Toxin Binding BBSRC
£0
 Sept. 22, 2019 Sept. 29, 2023 Active
12 On demand delivery of single molecules in living cells EPSRC
£0
 July 8, 2019 Jan. 8, 2023 Active
13 e-Infrastructure South Consortium - Centre for Innovation EPSRC
£5,660,000
 Jan. 1, 2012 March 30, 2012 Closed
14 An in vitro human cell assay to investigate the effects of psychiatric risk gene CACNA1C dosage on neuronal network activity MRC
£0
 Sept. 30, 2017 July 25, 2021 Closed
15 Molecular Mechanisms for a Novel Class of Openers Targeting Voltage- and Calcium-activated Potassium Channels. MRC
£0
 Sept. 30, 2016 March 29, 2021 Closed
16 Closed loop manufacture of bio-based polyester fibres for a circular bioeconomy BBSRC
£303,524
 Feb. 1, 2023 Jan. 31, 2025 Active
17 Analysis of mitochondrial homeostasis in ageing and neurodegeneration MRC
£1,682,908
 Aug. 31, 2015 Feb. 28, 2017 Closed
18 Analysis of mitochondrial homeostasis in ageing and neurodegeneration MRC
£5,943,575
 March 1, 2017 March 30, 2022 Active
19 Trafficking, storage and timely release of lipids: unfolding the fundamental mechanisms underlying metabolic reprogramming in pluripotent stem cells. BBSRC
£1,052,056
 July 23, 2017 Feb. 2, 2022 Closed
20 Trafficking, storage and timely release of lipids: unfolding the fundamental mechanisms underlying metabolic reprogramming in pluripotent stem cells. BBSRC
£322,778
 Oct. 19, 2019 Feb. 2, 2022 Closed
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