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Investigating how microcircuit abnormalities modulate brain-wide network dynamics to cause seizures across variant SCN1A mutations, using a zebrafish [Clear]

# Title Funder Funding Start End Status
41 Molecular basis of neurotransmission - cryo-EM structural and functional investigation of the human serotonin receptor in a lipid environment BBSRC
£0
 Sept. 26, 2021 Sept. 29, 2025 Active
42 Molecular basis of neurotransmission - cryo-EM structural and functional investigation of the human serotonin receptor in a lipid environment BBSRC
£0
 Sept. 30, 2021 Sept. 30, 2025 Active
43 The role of ion and proton transfer for the activation of GPCRs BBSRC
£0
 Sept. 2, 2018 Jan. 2, 2023 Active
44 Electrophysiological-mechanical coupled pulses in neural membranes: a new paradigm for clinical therapy of SCI and TBI (NeuroPulse) EPSRC
£0
 Sept. 30, 2017 June 29, 2021 Closed
45 Thermal sensory mechanisms involved in body temperature regulation BBSRC
£803,596
 May 31, 2014 May 30, 2017 Closed
46 Thermal sensory mechanisms involved in body temperature regulation BBSRC
£2,008,990
 May 31, 2014 May 31, 2017 Closed
47 An investigation of the bidirectional relationship between tau protein propagation and neural circuit activity in mouse models of Alzheimer's disease MRC
£0
 Sept. 26, 2021 Sept. 29, 2025 Active
48 The role of alpha3-GABAA receptors in mono-aminergic neuronal function BBSRC
£0
 Sept. 30, 2015 Sept. 29, 2019 Closed
49 Role of voltage-dependent calcium channels in nociceptive transmission under normal and neuropathic conditions BBSRC
£465,984
 Jan. 1, 2007 Dec. 31, 2009 Closed
50 Dynamic stochastic block modelling for analysing recombination in HIV FIC
£38,045
 March 31, 2020 Sept. 30, 2021 Closed
51 Training in hIPSC differentiation protocols to generate motor neuron-muscle cultures to replace rat models in study of mitochondria on axon physiology NC3Rs
£265,140
 Feb. 1, 2017 Jan. 31, 2019 Closed
52 Probing the dynamics of agonist drug interaction with Cys-loop channels by single-molecule recording MRC
£1,076,130
 Nov. 1, 2012 April 29, 2016 Closed
53 Glycosylphosphatidylinositol (GPI)-anchoring of calcium channel alpha2delta subunits: function and pharmacology MRC
£1,929,610
 April 30, 2011 Oct. 30, 2015 Closed
54 Artificial Intelligence 3D Biventricular Scar Modelling to Guide Precision VT Ablation MRC
£510,018
 Aug. 31, 2021 Aug. 30, 2024 Active
55 Understanding and reducing artefacts in simultaneously acquired EEG and fMRI data EPSRC
£678,358
 Feb. 1, 2012 July 30, 2015 Closed
56 Personalised thermal-fluid models for planning catheter ablation therapy for atrial arrhythmia EPSRC
£186,804
 Feb. 3, 2017 July 14, 2018 Closed
57 Imaging Membrane Potential via Second Harmonic Generation EPSRC
£1,578,386
 Aug. 31, 2010 Aug. 30, 2014 Closed
58 Voltage-independent calcium entry and its role in the differentiation of neuronal cancer cell phenotypes MRC
£677,434
 July 8, 2007 Nov. 8, 2010 Closed
59 Mitochondrial ubiquitin dynamics and apoptotic cell death. MRC
£2,794,620
 May 2, 2016 May 2, 2019 Closed
60 Chimeric Human-NavMs Sodium Channel Constructs for Structure/Function Studies of Selective Toxin Binding BBSRC
£0
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