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Exploitation of a Pharmacological 'Master Switch' to Probe the K+ Channel Selectivity Filter Gating Mechanism [Clear]

# Title Funder Funding Start End Status
1 Multi-protein assembly of intracellular ion-sensitive potassium channel complexes BBSRC
£465,868
 April 30, 2006 April 29, 2009 Closed
2 The lighter touch: minimally-invasive optical modulation of Ca2+-activated K+ ion channels EPSRC
£1,082,056
 June 30, 2007 Sept. 29, 2010 Closed
3 Co-operative gating interactions in the yeast TOK1 K+ channel BBSRC
£383,774
 Sept. 30, 2006 Jan. 31, 2009 Closed
4 Parallel electrophysiological characterization of sodium channels EPSRC
£1,067,438
 Sept. 30, 2010 Sept. 29, 2014 Closed
5 Parallel electrophysiological characterization of sodium channels EPSRC
£956,988
 May 31, 2010 May 30, 2014 Closed
6 Analysing GORK clustering for enhanced stomatal control BBSRC
£895,564
 May 30, 2015 May 29, 2018 Closed
7 Microsystems for coupled expression and electrophysiology of ion channels EPSRC
£203,872
 June 22, 2011 Nov. 29, 2013 Closed
8 Modulation of thermo-TRP ion channel activity by phosphorylation and trafficking to the membrane BBSRC
£779,192
 Jan. 1, 2008 Dec. 31, 2010 Closed
9 Modulation of thermo-TRP ion channel activity by phosphorylation and trafficking to the membrane BBSRC
£1,947,980
 Jan. 1, 2008 Dec. 31, 2010 Closed
10 Dissection of voltage-gated ion channel physiology in vivo in the C. elegans oxygen-sensing neural circuit MRC
£1,235,606
 Feb. 15, 2016 April 29, 2020 Closed
11 Directed control of secretory vesicle fusion BBSRC
£881,252
 June 16, 2013 June 15, 2016 Closed
12 Structure and Function of Voltage-Gated Ion Channels and their Applications for Rational Drug Design BBSRC
£1,064,830
 March 30, 2014 Sept. 29, 2018 Closed
13 Probing the dynamics of agonist drug interaction with Cys-loop channels by single-molecule recording MRC
£1,076,130
 Nov. 1, 2012 April 29, 2016 Closed
14 Effects of neurotransmitters on axonal KV7 channel function in hippocampal neurons BBSRC
£724,242
 April 29, 2014 July 30, 2018 Closed
15 Role of A- and M-type K+ and Ih currents and channels in spontaneous pain MRC
£748,288
 Dec. 1, 2007 May 30, 2011 Closed
16 Molecular mechanisms of voltage-gated potassium channel clustering in myelinated axons BBSRC
£1,173,476
 March 31, 2020 March 30, 2023 Active
17 Role of voltage-dependent calcium channels in nociceptive transmission under normal and neuropathic conditions BBSRC
£465,984
 Jan. 1, 2007 Dec. 31, 2009 Closed
18 Cellular Dynamics of Voltage-Gated Calcium Channels: Control Via Gabapentinoid-sensitive Auxiliary Alpha2-Delta Subunits MRC
£1,167,304
 Jan. 14, 2008 April 12, 2011 Closed
19 High permittivity dielectrics on Ge for end of Roadmap application EPSRC
£925,178
 March 31, 2011 Sept. 29, 2014 Closed
20 High permittivity dielectrics on Ge for end of Roadmap application EPSRC
£1,073,780
 March 31, 2011 March 30, 2014 Closed
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