| Feb. 13, 2024, 4:19 p.m. |
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[{"model": "core.projectfund", "pk": 61803, "fields": {"project": 9990, "organisation": 7, "amount": 462143, "start_date": "2020-01-01", "end_date": "2023-12-31", "raw_data": 175221}}]
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| Jan. 30, 2024, 4:24 p.m. |
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[{"model": "core.projectfund", "pk": 54649, "fields": {"project": 9990, "organisation": 7, "amount": 462143, "start_date": "2020-01-01", "end_date": "2023-12-31", "raw_data": 149572}}]
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| Jan. 2, 2024, 4:15 p.m. |
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[{"model": "core.projectfund", "pk": 47443, "fields": {"project": 9990, "organisation": 7, "amount": 462143, "start_date": "2020-01-01", "end_date": "2023-12-31", "raw_data": 130254}}]
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| Dec. 5, 2023, 4:23 p.m. |
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[{"model": "core.projectfund", "pk": 40194, "fields": {"project": 9990, "organisation": 7, "amount": 462143, "start_date": "2020-01-01", "end_date": "2023-12-31", "raw_data": 93986}}]
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| Nov. 27, 2023, 2:14 p.m. |
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{"external_links": []}
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectfund", "pk": 32896, "fields": {"project": 9990, "organisation": 7, "amount": 462143, "start_date": "2020-01-01", "end_date": "2023-12-31", "raw_data": 53377}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectorganisation", "pk": 94767, "fields": {"project": 9990, "organisation": 11633, "role": "COLLAB_ORG"}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectorganisation", "pk": 94766, "fields": {"project": 9990, "organisation": 12473, "role": "COLLAB_ORG"}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectorganisation", "pk": 94765, "fields": {"project": 9990, "organisation": 12474, "role": "COLLAB_ORG"}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectorganisation", "pk": 94764, "fields": {"project": 9990, "organisation": 10918, "role": "COLLAB_ORG"}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectorganisation", "pk": 94763, "fields": {"project": 9990, "organisation": 12475, "role": "COLLAB_ORG"}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectorganisation", "pk": 94762, "fields": {"project": 9990, "organisation": 11111, "role": "LEAD_ORG"}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectperson", "pk": 59481, "fields": {"project": 9990, "person": 14496, "role": "COI_PER"}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectperson", "pk": 59480, "fields": {"project": 9990, "person": 14497, "role": "COI_PER"}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectperson", "pk": 59479, "fields": {"project": 9990, "person": 14479, "role": "COI_PER"}}]
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| Nov. 21, 2023, 4:36 p.m. |
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[{"model": "core.projectperson", "pk": 59478, "fields": {"project": 9990, "person": 14498, "role": "PI_PER"}}]
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| Nov. 20, 2023, 2:04 p.m. |
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{"title": ["", "19-ERACoBioTech SYNBIOGAS: Synthetic landfill microbiomes for enhanced anaerobic digestion to biogas"], "description": ["", "\nLignocellulosic plant biomass is the most abundant waste product generated by society, agriculture and industry. By 2025, global cities will\ngenerate approximately 2.2 billion tonnes of solid waste biomass per year, with significant impacts upon health and the economy at both\nlocal and global scales. Natural communities of microorganisms (microbiomes) convert waste biomass to methane-rich biogas that can be\nused as a sustainable and renewable green-energy source to generate electricity, heat and power, and biomethane for injection into the\nnational gas grid and production of transport fuels. Anaerobic digestion (AD) plants and landfill sites are engineered environments where\nthese microbial processes are harnessed for waste decomposition and biogas production. The EU is the largest global producer of biogas\nfrom biomass, with over 17,000 AD plants, and consequently, the microbiological conversion of solid waste residues to biogas in AD plants\nand landfill sites presents an unprecedented opportunity to leverage key enabling technologies for a sustainable bio-based economy for\ngreen-energy production. In turn, conversion of waste biomass to biomethane will mitigate the escalating environmental and social impacts\nof waste residues. However, the metabolic function of microorganisms responsible for anaerobic digestion is poorly understood, and most\nprevious studies have focused on animal gut microorganisms that are typically used to incoluate microorganisms into anaerobic digestion\nplants as slurry. One of the major bottlenecks to industrial application of microorganisms for biomass-conversion is low substrate specificity,\nlow temperature tolerance, and an inability to perform optimally under reaction conditions. Natural microorganisms found in landfill sites\nrepresent an unexplored repository of biomass-degrading enzyme diversity with the potential to enhance existing industrial\nbiomass-conversion processes. Landfill microorganisms are already adapted to engineered environments, mineralise diverse solid waste\ntypes, produce methane-rich biogas, and are therefore good candidates for the bioaugmentation of anaerobic digestion processes. The SYNBIOGAS consortium is an academic-industry partnership that will integrate diverse and cutting-edge technological, analytical,\nengineering and computational approaches for characterisation of the landfill biomass-degrading microbiome. Microbial isolations, DNA\nsequencing, enzyme characterisation and computational modelling of landfill microbial biomass-conversion processes will inform the design\nand validation of optimised synthetic landfill microbiomes (SLMs) for enhanced waste biomass-conversion in AD plants and landfill sites, and\nto develop applications of the SLM that can be readily adopted by industry. Engineering biomass-degrading microbiomes is a new research\nfrontier with many novel applications, including bioaugmentation and optimisation of biomass conversion in AD and landfill systems towards\nan enhanced bio-based economy for waste management, environmental protection, and sustainable intensification of renewable energy\ngeneration.\n\n"], "extra_text": ["", "\nTechnical Abstract:\nThe landfill microbiome represents an unexplored repository of biomass-degrading enzyme diversity to enhance existing industrial\nbiomass-conversion processes and identify new hydrolase enzymes of relevance for industrial biotechnology processes. This project aims to utilise a systems biology analysis of biomass-conversion by landfill microbiota, combining novel technological, analytical and computational approaches for microbiome characterisation, in silico discovery and validation of novel enzymes, and process modelling for the design of optimal synthetic biomass-converting microbiomes. Ultimately, the research will generate synthetic landfill microbiomes (SLMs) designed for bioaugmentation of landfill sites and anaerobic digestion plants for enhanced biomass conversion and biogas generation, enabling a progression in TRL in this sector. In addition, we will utilise life cycle assessment and cost benefit analysis approaches to demonstrate the potential industrial benefits of our process model and synthetic microbiome, and will generate a road map for industry adoption of the new technology. The research leverages new approaches to understanding fundamental questions regarding the ecological factors that drive syntrophic interactions between anaerobic biomass-degrading microbiota.\n\nPotential Impact:\nThe landfill microbiome represents an unexplored repository of biomass-degrading enzyme diversity to enhance existing industrial\nbiomass-conversion processes and identify new hydrolase enzymes of relevance for industrial biotechnology processes (Ransom-Jones et al.,\n2017). This project will provide the first systems biology analysis of biomass-conversion by landfill microbiota (WP1-3) combining novel\ntechnological, analytical and computational approaches for microbiome characterisation (WP1), in silico discovery and validation of novel\nenzymes (WP2) and process modelling for the design of optimal synthetic biomass-converting microbiomes (WP3). Ultimately, the research\nin WP's 1-3 will generate synthetic landfill microbiomes (SLMs) designed for bioaugmentation of landfill sites and anaerobic digestion\nplants for enhanced biomass conversion and biogas generation in WP4, enabling a progression from TRL2 to TRL6 through the project\n(Figure 2). In WP5, we subsequently utilise life cycle assessment and cost benefit analysis approaches to demonstrate the potential\nindustrial benefits of our process model and synthetic microbiome, and will generate a road map for industry adoption of the new\ntechnology. The research leverages new approaches to understanding fundamental questions regarding the ecological factors\nthat drive syntrophic interactions between anaerobic biomass-degrading microbiota.\nSynthetic biology approaches for the engineering of biomass-degrading microbiomes is a new research frontier with many\nnovel applications, including bioaugmentation and optimisation of biomass conversion in AD systems towards an enhanced bio-based\neconomy for waste management, environmental protection and sustainable intensification of renewable energy generation.\nPreviously, laboratory-based landfill bioreactor experiments undergoing bioaugmentation with natural compost microorganisms demonstrated improved biomass degradation from 65% to 99%, and increased biogas generation (Kinet et al., 2016). The success of\nbioaugmentation for biomass conversion with relatively undefined microbial populations from natural environments in laboratory reactors is\nencouraging; however, such approaches have not been extensively validated and demonstrated in relevant industrial environments (i.e. AD\nplants and landfills), and SLMs have not previously been designed and tested. Consequently, the opportunity to (i) directly manipulate\nbiomass-converting microbiota through characterisation, process modelling and the design of more sophisticated synthetic microbiomes,\nand (ii), industrial application/validation of SLMs for enhanced biogas generation, in the SYNBIOGAS project is a tantalising challenge, with\nsignificant potential to provide a paradigm shift in waste biomass conversion, green-energy production and waste management.\nThe SYNBIOGAS project is directly relevant to the CoBioTech call, and will develop a biotechnological application (synthetic landfill\nmicrobial communities for enhanced biomass conversion to biogas) with potential for strong economic and social impacts towards at\nsustainable bio-based economy. Our integration and development of the approach with industry partners ensures that our research has high\npotential for commercialisation and industry adoption through achieving high levels of technology readiness (TRL 2-6). Social impacts\ninclude sustainable options for waste management, reduce environmental impact of waste biomass, and the development of key enabling\ntechnologies for sustainable green-energy generation with key economic benefits. Tangible outputs would include: novel CAZYmes with\nenhanced catalytic activity and substrate specificity; high resolution datasets on SLM activity; world-leading metabolic process models of\nanaerobic digestion processes; validated biotechnological applications of SLMs for AD bioaugmentation; life cycle assessment and a\nstakeholder roadmap for technology implementation.\n\n\n"], "status": ["", "Active"]}
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| Nov. 20, 2023, 2:04 p.m. |
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{"external_links": [41302]}
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| Nov. 20, 2023, 2:04 p.m. |
Created
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[{"model": "core.project", "pk": 9990, "fields": {"owner": null, "is_locked": false, "coped_id": "b3d91955-5d12-4dbc-ae98-4d3a21580afe", "title": "", "description": "", "extra_text": "", "status": "", "start": null, "end": null, "raw_data": 53360, "created": "2023-11-20T13:37:06.761Z", "modified": "2023-11-20T13:37:06.761Z", "external_links": []}}]
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