History of changes to: Microscale devices for detection of key pollutants in the built environment
Date Action Change(s) User
Nov. 27, 2023, 2:11 p.m. Added 35 {"external_links": []}
Nov. 20, 2023, 2:02 p.m. Added 35 {"external_links": []}
Nov. 13, 2023, 1:32 p.m. Added 35 {"external_links": []}
Nov. 6, 2023, 1:30 p.m. Added 35 {"external_links": []}
Aug. 14, 2023, 1:30 p.m. Added 35 {"external_links": []}
Aug. 7, 2023, 1:31 p.m. Added 35 {"external_links": []}
July 31, 2023, 1:33 p.m. Added 35 {"external_links": []}
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July 17, 2023, 1:33 p.m. Added 35 {"external_links": []}
July 10, 2023, 1:25 p.m. Added 35 {"external_links": []}
July 3, 2023, 1:25 p.m. Added 35 {"external_links": []}
June 26, 2023, 1:25 p.m. Added 35 {"external_links": []}
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June 5, 2023, 1:32 p.m. Added 35 {"external_links": []}
May 29, 2023, 1:27 p.m. Added 35 {"external_links": []}
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April 3, 2023, 1:25 p.m. Added 35 {"external_links": []}
Jan. 28, 2023, 11:08 a.m. Created 43 [{"model": "core.projectfund", "pk": 22903, "fields": {"project": 84, "organisation": 5, "amount": 98809, "start_date": "2015-05-31", "end_date": "2016-05-30", "raw_data": 37854}}]
Jan. 28, 2023, 10:51 a.m. Added 35 {"external_links": []}
April 11, 2022, 3:44 a.m. Created 43 [{"model": "core.projectfund", "pk": 15000, "fields": {"project": 84, "organisation": 5, "amount": 98809, "start_date": "2015-05-31", "end_date": "2016-05-30", "raw_data": 5190}}]
April 11, 2022, 3:44 a.m. Created 41 [{"model": "core.projectorganisation", "pk": 56960, "fields": {"project": 84, "organisation": 1568, "role": "PP_ORG"}}]
April 11, 2022, 3:44 a.m. Created 41 [{"model": "core.projectorganisation", "pk": 56959, "fields": {"project": 84, "organisation": 96, "role": "LEAD_ORG"}}]
April 11, 2022, 3:44 a.m. Created 40 [{"model": "core.projectperson", "pk": 35078, "fields": {"project": 84, "person": 1757, "role": "RESEARCH_PER"}}]
April 11, 2022, 3:44 a.m. Created 40 [{"model": "core.projectperson", "pk": 35077, "fields": {"project": 84, "person": 1758, "role": "COI_PER"}}]
April 11, 2022, 3:44 a.m. Created 40 [{"model": "core.projectperson", "pk": 35076, "fields": {"project": 84, "person": 1759, "role": "PI_PER"}}]
April 11, 2022, 1:46 a.m. Updated 35 {"title": ["", "Microscale devices for detection of key pollutants in the built environment"], "description": ["", "\nPolar volatile organic compounds (pVOC) have a profound impact on the functioning of the atmosphere and many are also toxic airborne pollutants. They are however very difficult to measure, being sticky, reactive and in some cases thermally unstable. These same species are also very significant in the built environment, negatively influencing indoor air quality, malodours, human health and contributing to costly effects such as sick building syndrome. Through previous NERC support we developed a unique microfluidic approach to measuring trace levels of pVOCs in the atmosphere. We achieved this using a novel lab-on-a-chip technology that allows for a highly efficient chemical derivatization of pVOCs in the gas phase, which in simple terms converts the target molecules into more stable forms that are much easier to detect. Once derivatised, pVOCs can then be measured using common analytical techniques such as gas chromatography and mass spectrometry, instruments that are found in most modern chemical laboratories.\n\nThe key to our new technology is a micro-reactor that integrates together three laboratory functions: (1) a gas and liquid mixer and reactor, where derivatization takes place, (2) controlled reagent heating to speed up the analysis, and (3) sample pre-concentration to enable lower detection limits. The output from the micro-reactor is a microlitre effluent stream of processed sample that has stripped the pVOCs from the gas phase into a stable and highly concentrated liquid form, and that is ready for direct introduction to Gas Chromatography-Mass Spectrometry (GC-MS) or other technique. The micro-reactor can be completely automated and provides a highly effective solution to an otherwise multi-step, manual analytical procedure by providing a fast and highly efficient derivatization reaction at elevated temperatures, and using very low chemical volumes\n\nThe assessment of pVOCs in the gas phase in the built environment is a widespread problem with significant economic impacts, and for which here are few effective technical solutions. These chemicals are emitted from furniture, carpets, paints and building construction materials in general and there have been significant new regulatory requirements introduced in the EU, USA and China in recent years that have created a major but as yet unmet demand for simple and efficient measurement methods. Any product sold for the built environment in the EU must comply with the very recent 2013 Construction Productn Regulation Directives before it can be put on sale and a supplier must demonstrate this either by testing their products in-house, or outsourcing the analysis to third-party laboratories. \n\nOur proposed innovation for follow-on funding is therefore to take a technology developed for a niche area of atmospheric chemistry and translate this into a urgently required turn-key sample preparative product for the analytical industries associated with gaseous emissions materials testing and the built environment. We plan to complete the technical implementation of a fully functional prototype device and work with commercial partners to develop demonstration activities for particular industriesWe identify that the global market for such specialised analytical devices is relatively modest (measured in hundreds to low thousands of units), but that the improved lower-cost testing leads to improved product competitiveness, with much wider economic impacts . The societal and economic impact of the innovation should therefore be viewed more widely than simply the commercial revenue that might be obtained from device sales alone.\n\n"], "extra_text": ["", "\n\nPotential Impact:\nAn improved ability to detect pVOCs ultimately has benefits for public health, since their control and regulation is for reasons of health and well-being. The recent introduction of new regulations reflects both the growing body of evidence about health impacts (such as respiratory disease and long term cancer risk) and is a response to the increasing risk of accumulation of chemicals within buildings as they become more airtight as a consequence of energy efficiency measures. Improved testing of a wider range of chemicals is therefore likely to lead to more general reductions in VOC exposure within homes and workplaces.\n\nInstrumental methods to detect difficult-to-measure chemicals are essential to the functioning of a wide range of laboratory and field applications, and there is potential for our innovative analytical device to operate in many different markets that require the measurement of polar compounds in gas phase matrices. These markets include flavour and fragrances, fuels and lubricants, security and defence and personalised healthcare, all of which have some critical dependencies on knowing volatile organic compound composition in gas phase mixtures. We are specifically prioritising however small carbonyl compounds, since these are commonly emitted (and accumulate) within the built environment, and are subject to recent legislative changes that demand improved measurements from suppliers of materials for use indoors due to their impact on the health and wellbeing of individuals. We see this as a uniquely timely opportunity to introduce new ideas and concepts developed for atmospheric chemistry research into a new discipline area, and we have a technical solution to a difficult measurement problem that is more automated, more sensitive and has lower operating costs than competing approaches. We prioritise the development of a micro-fluidic derivatising tool as an turn-key peripheral device, since this matches well with existing supply pathways and allows us to retrofit onto existing standard laboratory GC-MS as well as support integrated new equipment bundles. \n\nFor the in-house and contract laboratories who adopt our technology, this will improve the ability to detect trace levels of key chemicals, increase sample throughput and, by extension, reduce the cost per analysis. The availability of an automated and lower-cost methodology will lower barriers to market for the supply chain associated with the built environment. Since all materials to be sold for use in the EU now require testing, the measurement requirement and its associated costs become a barrier to new product introductions, particularly for smaller companies without in-house testing capabilities. For such companies, an improved analytical methodology, which can be used in-house or procured from contract laboratories, will help overcome the regulatory hurdles for VOC emissions and so bring products to market at lower cost.\n\n\n"], "status": ["", "Closed"]}
April 11, 2022, 1:46 a.m. Added 35 {"external_links": [180]}
April 11, 2022, 1:46 a.m. Created 35 [{"model": "core.project", "pk": 84, "fields": {"owner": null, "is_locked": false, "coped_id": "5156b729-7566-415c-8e35-29abd6694e57", "title": "", "description": "", "extra_text": "", "status": "", "start": null, "end": null, "raw_data": 5175, "created": "2022-04-11T01:28:53.130Z", "modified": "2022-04-11T01:28:53.130Z", "external_links": []}}]