Title
Surfglyco

CoPED ID
00640bf1-07de-4062-bb37-fd6b6f700e82

Status
Closed


Value
£130,434

Start Date
April 30, 2016

End Date
July 30, 2019

Description

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Surfactants are surface-active molecules which we encounter daily for instance in cleaning agents or personal care products. The major amount of surfactants is still produced petro-chemically. Surfactants from chemical synthesis based on renewables are on the rise but the required oils originate from tropical plants. Thus there is a special interest in new tailor-made, biodegradable
surfactants from renewable substrate flexible processes with native European sustainable resources. Natural biosurfactants, especially glycolipids, can be produced using microbial or
enzymatic processes which results in a wide range of molecules with varying sugar groups and hydrophobic lipid moieties. Their unique molecular structure often leads to beneficial effects which create an added value for the desired applications. Only few microbial glycolipids are already manufactured on an industrial scale due to a low microbial productivity of desired glycolipid derivatives and a cost-intensive downstream processing. One aim
of SurfGlyco is to enhance the potential of the underexploited microbial glycolipids which show promising yields and an enormous molecular variability. By adjusted feeding strategies and fermentations connected to an effective downstream processing we want to produce tailor-made biosurfactants with optimized performance in various market areas. As second aim SurfGlyco will generate novel glycolipids of varying sugar and lipid components by using highly selective enzymatic reactions under mild reaction conditions. Currently, enzymatic synthesis still suffers from low space-time yields and a narrow range of products. SurfGlyco wants to overcome these problems by using stable enzymes with altered substrate specificities and the use of deep eutectic solvents as
non-toxic reaction media which recently have been shown to enable high glycolipid yields.

Croda Europe Limited LEAD_ORG
Croda Europe Limited PARTICIPANT_ORG

Subjects by relevance
  1. Lipids
  2. Biotechnology
  3. Surface-active agents

Extracted key phrases
  1. Active molecule
  2. Surfglyco
  3. Microbial glycolipid
  4. High glycolipid yield
  5. Renewable substrate flexible process
  6. Low microbial productivity
  7. Personal care product
  8. Selective enzymatic reaction
  9. Glycolipid derivative
  10. Novel glycolipid
  11. Second aim SurfGlyco
  12. Surfactants
  13. Effective downstream processing
  14. Enzymatic synthesis
  15. Enzymatic process

Related Pages

UKRI project entry

UK Project Locations