History of changes to: The lighter touch: minimally-invasive optical modulation of Ca2+-activated K+ ion channels
Date Action Change(s) User
Nov. 27, 2023, 2:12 p.m. Added 35 {"external_links": []}
Nov. 20, 2023, 2:03 p.m. Added 35 {"external_links": []}
Nov. 13, 2023, 1:33 p.m. Added 35 {"external_links": []}
Nov. 6, 2023, 1:31 p.m. Added 35 {"external_links": []}
Aug. 14, 2023, 1:30 p.m. Added 35 {"external_links": []}
Aug. 7, 2023, 1:31 p.m. Added 35 {"external_links": []}
July 31, 2023, 1:34 p.m. Added 35 {"external_links": []}
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July 17, 2023, 1:34 p.m. Added 35 {"external_links": []}
July 10, 2023, 1:26 p.m. Added 35 {"external_links": []}
July 3, 2023, 1:26 p.m. Added 35 {"external_links": []}
June 26, 2023, 1:25 p.m. Added 35 {"external_links": []}
June 19, 2023, 1:27 p.m. Added 35 {"external_links": []}
June 12, 2023, 1:29 p.m. Added 35 {"external_links": []}
June 5, 2023, 1:33 p.m. Added 35 {"external_links": []}
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April 10, 2023, 1:25 p.m. Added 35 {"external_links": []}
April 3, 2023, 1:26 p.m. Added 35 {"external_links": []}
Jan. 28, 2023, 11:08 a.m. Created 43 [{"model": "core.projectfund", "pk": 27144, "fields": {"project": 4338, "organisation": 2, "amount": 541028, "start_date": "2007-06-30", "end_date": "2010-09-29", "raw_data": 43005}}]
Jan. 28, 2023, 10:52 a.m. Added 35 {"external_links": []}
April 11, 2022, 3:47 a.m. Created 43 [{"model": "core.projectfund", "pk": 19253, "fields": {"project": 4338, "organisation": 2, "amount": 541028, "start_date": "2007-06-30", "end_date": "2010-09-29", "raw_data": 20262}}]
April 11, 2022, 3:47 a.m. Created 41 [{"model": "core.projectorganisation", "pk": 73403, "fields": {"project": 4338, "organisation": 1047, "role": "LEAD_ORG"}}]
April 11, 2022, 3:47 a.m. Created 40 [{"model": "core.projectperson", "pk": 45116, "fields": {"project": 4338, "person": 6276, "role": "COI_PER"}}]
April 11, 2022, 3:47 a.m. Created 40 [{"model": "core.projectperson", "pk": 45115, "fields": {"project": 4338, "person": 6277, "role": "PI_PER"}}]
April 11, 2022, 1:47 a.m. Updated 35 {"title": ["", "The lighter touch: minimally-invasive optical modulation of Ca2+-activated K+ ion channels"], "description": ["", "\nVoltage-gated ion channels are small pores that enable the flow of important chemical ions, such as calcium (Ca2+) and potassium (K+) in and out of cells, under the application of a small voltage. These gates play a vital role in a range of physiological processes and form a key element in the development of new drugs and delivery methods. At the moment, voltage-gated ion channel activity is controlled by thrusting an electrode into a cell excised from a human or animal in order to activate the channel and record electrical activity. This is, however, a thoroughly invasive process and it is a difficult technique to master. This proposal will investigate the use of a laser source to open voltage-gated ion channels in a minimally invasive manner. By shining the laser source - which is effectively a very high electric field - onto the cell, sufficient voltage to activate the ion channel will be provided. We will investigate Ca2+-activated K+ ion channels, but the proposed minimally-intrusive method will have potential application across a wider range of voltage-gated ion channels.\n\n"], "extra_text": ["", "\n\n\n\n"], "status": ["", "Closed"]}
April 11, 2022, 1:47 a.m. Added 35 {"external_links": [16381]}
April 11, 2022, 1:47 a.m. Created 35 [{"model": "core.project", "pk": 4338, "fields": {"owner": null, "is_locked": false, "coped_id": "78d605b0-b667-4484-9497-d45ea0dcd6a9", "title": "", "description": "", "extra_text": "", "status": "", "start": null, "end": null, "raw_data": 20247, "created": "2022-04-11T01:38:24.849Z", "modified": "2022-04-11T01:38:24.849Z", "external_links": []}}]