Flexible Engineered Solutions for Xylose Metabolism using Synthetic Biology (FLEX)

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Title
Flexible Engineered Solutions for Xylose Metabolism using Synthetic Biology (FLEX)

CoPED ID
2fff14c5-6f24-4c8e-85aa-6031c3faebf7

Status
Closed


Value
£1,058,470

Start Date
July 31, 2013

End Date
July 31, 2015

Description

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With concerns over the future of natural resources and energy security there is a growing need for the UK to develop renewable and sustainable sources of chemicals such as butanol, a key precursor in the production of paints, polymers and plastics. Bio-butanol can also be used as a biofuel, directly replacing gasoline or blended with diesel and with many advantages over ethanol. However in order for these bio-based chemicals to compete with oil derivatives we need to improve the range of cheap, sustainable feedstocks that can be fermented by solventogenic microbes, and the efficiency of this fermentation process. Current commercial processes require the use of extreme heat and harsh chemicals to convert agricultural waste material to simple fermentable sugars. This not only reduces the environmental benefits of renewables but also makes the fermentation of waste feedstocks less economic when compared with easier substrates such as starch. We are developing microbial strains that are able to use agricultural wastes that have undergone less intensive pre-treatment procedures to produce bio-butanol with high efficiency, thereby reducing the environmental impact of harsh chemical and high temperature processes and reducing the competition for food crops as fermentation substrates.

GREEN BIOLOGICS LIMITED LEAD_ORG
BIOCLEAVE LIMITED PARTICIPANT_ORG
UNIVERSITY OF YORK PARTICIPANT_ORG
GREEN BIOLOGICS LIMITED PARTICIPANT_ORG

Karen Stanley PM_PER

Subjects by relevance
  1. Environmental effects
  2. Biofuels
  3. Sustainable development
  4. Renewable energy sources
  5. Wastes
  6. Natural resources
  7. Fermentation (metabolism)
  8. Safety and security
  9. Polymers

Extracted key phrases
  1. Flexible Engineered Solutions
  2. Synthetic Biology
  3. Xylose Metabolism
  4. Use
  5. Harsh chemical
  6. High temperature process
  7. Agricultural waste material
  8. Fermentation process
  9. FLEX
  10. Current commercial process
  11. Waste feedstock
  12. Sustainable feedstock
  13. Natural resource
  14. High efficiency
  15. Fermentation substrate

Related Pages

UKRI project entry

UK Project Locations